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AstraZeneca CEO Pascal Soriot on why he’s building in the U.S.: ‘Europe is losing ground’

Good morning. Thirty-three days. That’s how long it took from the time AstraZeneca CEO Pascal Soriot greeted Virginia Governor Glenn Youngkin in his London office to announcing a $4 billion manufacturing facility in the state at a press conference in Washington yesterday. Soriot said it’s the European pharma giant’s largest-ever single manufacturing investment, negotiated at the fastest-ever speed. “Usually, this kind of discussion takes months,” he told me in D.C. “Sometimes you have a meeting of minds.”

One thing that Soriot shares with the governor, not to mention other European pharma rivals, is an understanding that it’s important to visibly invest in the U.S. right now. AstraZeneca’s announcement is part of a $50 billion commitment to new U.S. facilities by 2030, much like the tens of billions in spending recently announced by Roche, Novartis, and Sanofi—and billions announced by their U.S. rivals.

The threat of tariffs is a factor in beefing up AstraZeneca’s U.S. manufacturing, of course, but Soriot says the investments make sense on other levels. “Our pipeline is moving quickly,” he told me. That’s especially true when it comes to the market for innovative weight-management drugs like oral GLP-1, which will be manufactured at the facility site, which has not yet been named. “Our bet is the U.S. economy will continue to grow and the U.S. will continue to dominate innovation.” 

Then again, Soriot noted that China is also innovating fast. The drugmaker is investing billions there to beef up R&D and presumably help sway the political winds in his company’s favor.

If anywhere is falling out of favor for AstraZeneca as a place to produce new drugs, it’s the company’s home continent. “Europe is losing ground,” he said. “They’re focused more on social benefits and managing costs. It’s like one company is trying to drive the top line, creating opportunities and economic growth, while another company is trying to manage costs and staying flat on the top line. That doesn’t work.”

Contact CEO Daily via Diane Brady at diane.brady@fortune.com

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From the analysts

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JPMorgan on the tariffs: “The tariff announcements over the last few weeks are broader and higher. While those on Vietnam and Indonesia were in line with expectations, the additional tariffs on Brazil, Canada, and Mexico were not. Nor was the higher 50% rate on copper. Consequently, if these tariffs (along with the extensions to semiconductors, lumber, and pharmaceuticals) are realized, then the effective tariff rate could well exceed 20% (Figure 1). All eyes are therefore on 1 August, which is the new deadline set by the administration for countries to finalize trade deals,” Jahangir Aziz, and Bruce Kasman.

Goldman Sachs on mortgages: “Sustained higher mortgage rates will continue to have their most pronounced impact on housing turnover. 87% of mortgage borrowers have interest rates below current market rates, and 66% have rates 2pp below market rates, strongly disincentivizing them from moving. As a result, we expect annual existing home sales of just 4.1mn, 23% below 2019 levels but in line with the pace of the last two years,” per Ronnie Walker et al.

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CEO Daily is compiled and edited by Joey Abrams and Jim Edwards.

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